Tmem184b^{Gt(IST10294F4)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Tmem184b^{Gt(IST10294F4)Tigm}
• Name: transmembrane protein 184b; gene trap IST10294F4, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:3941678
• Gene: Tmem184b Location: Chr15:79244884-79287503 bp, - strand Genetic Position: Chr15, 37.7 cM
• Alliance: Tmem184b^{Gt(IST10294F4)Tigm} page

Mutation origin

• Mutant Cell Line: IST10294F4
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Hypomorph)
• Mutation: Insertion of gene trap vector Vector: VICTR76 Vector Type: gene trap
• Mutation details: The gene is disrupted by a gene-trap cassette between the first and second exons. Quantitative PCR analysis revealed a ~20-fold reduction of RNA expression in adult brain tissue from homozygous mutant mice.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST10294F4BBF1	EF734239 ; (MGI Seq Detail)	inverse PCR	Chr15:79280275-79280514 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  33 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Tmem184b Mutation: 36 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)