Poglut1^{Gt(IST10323G11)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Poglut1^{Gt(IST10323G11)Tigm}
• Name: protein O-glucosyltransferase 1; gene trap IST10323G11, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:3942939
• Synonyms: Ktelc1^{Gt(IST10323G11)Tigm}, Rumi^betaGeo
• Gene: Poglut1 Location: Chr16:38345499-38370620 bp, - strand Genetic Position: Chr16, 26.86 cM
• Alliance: Poglut1^{Gt(IST10323G11)Tigm} page

Mutation origin

• Mutant Cell Line: IST10323G11
• Germline Transmission: Earliest citation of germline transmission: J:171432
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: VICTR76 Vector Type: gene trap
• Mutation details: A single gene trap insertion occurred in intron 2. RT-PCR on liver extracts from heterozygous mice showed a 50% decrease in mRNA levels. Immunoblot analysis failed to detect protein expression in homozygous mice. (J:171432)
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST10323G11BBF1	EF742275 ; (MGI Seq Detail)	inverse PCR	Chr16:38369682-38370234 bp (+)
  IST10323G11HMF1	EF735804 ; (MGI Seq Detail)	inverse PCR	Chr16:38369682-38369824 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  71 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Poglut1 Mutation: 61 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)