Babam1^{Gt(IST11207B9)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Babam1^{Gt(IST11207B9)Tigm}
• Name: BRISC and BRCA1 A complex member 1; gene trap IST11207B9, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:3994220
• Synonyms: M40^-, Merit40^-
• Gene: Babam1 Location: Chr8:71849505-71857263 bp, + strand Genetic Position: Chr8, 34.43 cM, cytoband C1
• Alliance: Babam1^{Gt(IST11207B9)Tigm} page

Mutation origin

• Mutant Cell Line: IST11207B9
• Germline Transmission: Earliest citation of germline transmission: J:223526
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: VICTR76 Vector Type: gene trap
• Mutation details: Mutant mice were generated by a gene trap insertion between exons 1 and 2, 5' to the start codon. Decreased transcript level was shown by RT-PCR, and the encoded protein was undetectable in homozygous mutant mouse embryonic fibroblasts (MEFs), as shown by Western blotting. (J:238472)
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST11207B9HMF1	EF812986 ; (MGI Seq Detail)	inverse PCR	Chr8:71849536-71850026 bp (-)
  IST11207B9BBF1	EF806007 ; (MGI Seq Detail)	inverse PCR	Chr8:71849554-71850026 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  7 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Babam1 Mutation: 22 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)