Slc25a32^{Gt(IST11480G10)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Slc25a32^{Gt(IST11480G10)Tigm}
• Name: solute carrier family 25, member 32; gene trap IST11480G10, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:4011881
• Synonyms: Slc25a32^gt
• Gene: Slc25a32 Location: Chr15:38954626-38976111 bp, - strand Genetic Position: Chr15, 15.39 cM
• Alliance: Slc25a32^{Gt(IST11480G10)Tigm} page

Mutation origin

• Mutant Cell Line: IST11480G10
• Germline Transmission: Earliest citation of germline transmission: J:261656
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: VICTR76 Vector Type: gene trap
• Mutation details: A gene trap vector containing a beta-geo reporter gene inserted between exons 1 and 2, resulting in a loss-of-function mutation. RT-PCR confirmed the absence of mRNA expression in E10 homozygous mutant embryos. No encoded protein was detected in isolated mitochondria from E11.5 mutant embryos by immunoblot analysis. (J:261656)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST11480G10HMF1	EF830772 ; (MGI Seq Detail)	inverse PCR	Chr15:38975181-38975625 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  3 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Slc25a32 Mutation: 20 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)