Mcu^{Gt(IST11669F8)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Mcu^{Gt(IST11669F8)Tigm}
• Name: mitochondrial calcium uniporter; gene trap IST11669F8, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:4022473
• Gene: Mcu Location: Chr10:59282806-59452514 bp, - strand Genetic Position: Chr10, 29.55 cM
• Alliance: Mcu^{Gt(IST11669F8)Tigm} page

Mutation origin

• Mutant Cell Line: IST11669F8
• Germline Transmission: Earliest citation of germline transmission: J:208297
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: VICTR76 Vector Type: gene trap
• Mutation details: The gene trap vector inserted into intron 1. Western blot analysis confirmed the absence of protein expression in the skeletal muscle, liver and heart. (J:208297)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST11669F8BBF1	EF844953 ; (MGI Seq Detail)	inverse PCR	Chr10:59392993-59393040 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  12 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mcu Mutation: 27 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 16 reference(s)