Mir142hg^{Gt(IST11580H2)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Mir142hg^{Gt(IST11580H2)Tigm}
• Name: Mir142 host gene (non-protein coding); gene trap IST11580H2, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:4059881
• Synonyms: miR-142^-, miR-142^lacZ
• Gene: Mir142hg Location: Chr11:87646399-87648102 bp, + strand Genetic Position: Chr11, 52.21 cM
• Alliance: Mir142hg^{Gt(IST11580H2)Tigm} page

Mutation origin

• Mutant Cell Line: IST11580H2
• Germline Transmission: Earliest citation of germline transmission: J:194625
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: VICTR76 Vector Type: gene trap
• Mutation details: The beta-geo-containing gene trap inserted into the single intron. The insertion prevents transcription of Mir142 downstream of the insertion site but within the same intron. RT-PCR confirmed the absence of Mir142 trancript expression in dendritic cells. (J:213199)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST11580H2BBF1	EF898741 ; (MGI Seq Detail)	inverse PCR	Chr11:87647066-87647636 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  3 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir142hg Mutation: 3 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 7 reference(s)