Ggnbp2^{Gt(IST12476F10)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Ggnbp2^{Gt(IST12476F10)Tigm}
• Name: gametogenetin binding protein 2; gene trap IST12476F10, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:4072637
• Gene: Ggnbp2 Location: Chr11:84723187-84761643 bp, - strand Genetic Position: Chr11, 51.34 cM
• Alliance: Ggnbp2^{Gt(IST12476F10)Tigm} page

Mutation origin

• Mutant Cell Line: IST12476F10
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: VICTR76 Vector Type: gene trap
• Mutation details: The mutation is the insertion of a gene-trap vector LacZ/Neo cassette into the intron between exons 7 and 8 of the gene. The LacZ reporter was not expressed in-frame. RT-PCR showed the complete loss of encoded transcripts in null mutant embryos. (J:232444)
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST12476F10BBF1	JM199903 ; (MGI Seq Detail)	inverse PCR	Chr11:84736985-84737137 bp (-)
  IST12476F10BBF1	EF917762 ; (MGI Seq Detail)	inverse PCR	Chr11:84736985-84737137 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  57 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Ggnbp2 Mutation: 61 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)