Slc47a1^{Gt(IST12634F2)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Slc47a1^{Gt(IST12634F2)Tigm}
• Name: solute carrier family 47, member 1; gene trap IST12634F2, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:4100843
• Gene: Slc47a1 Location: Chr11:61234227-61269171 bp, - strand Genetic Position: Chr11, 37.96 cM
• Alliance: Slc47a1^{Gt(IST12634F2)Tigm} page

Mutation origin

• Mutant Cell Line: IST12634F2
• Germline Transmission: Earliest citation of germline transmission: J:206792
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted into intron 10. RT-PCR confirmed a 90% reduction in transcript expression in the liver and kidney. (J:206792)
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST12634F2BBF1	EF955362 ; (MGI Seq Detail)	inverse PCR	Chr11:61252293-61252682 bp (+)
  IST12634F2HMF1	EF962214 ; (MGI Seq Detail)	inverse PCR	Chr11:61252312-61252565 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  4 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Slc47a1 Mutation: 44 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)