Ppp2r5a^{Gt(IST13127C10)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Ppp2r5a^{Gt(IST13127C10)Tigm}
• Name: protein phosphatase 2, regulatory subunit B', alpha; gene trap IST13127C10, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:4119929
• Synonyms: B56alpha^hm
• Gene: Ppp2r5a Location: Chr1:191084178-191129238 bp, - strand Genetic Position: Chr1, 96.28 cM
• Alliance: Ppp2r5a^{Gt(IST13127C10)Tigm} page

Mutation origin

• Mutant Cell Line: IST13127C10
• Germline Transmission: Earliest citation of germline transmission: J:254808
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Hypomorph)
• Mutation: Insertion of gene trap vector Vector: VICTR76 Vector Type: gene trap
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. According to qRT-PCR the gene is expressed at 0.01-0.2% of control levels in various tissues, skin and MEFs and is thus concidered a hypomorphic allele.
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST13127C10HMF1	EF983950 ; (MGI Seq Detail)	inverse PCR	Chr1:191126946-191127362 bp (+)
  IST13127C10BBF1	EF984381 ; (MGI Seq Detail)	inverse PCR	Chr1:191126946-191127086 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  22 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 1 line available
• Carrying any Ppp2r5a Mutation: 24 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)