Aggf1^Gt(PT036)Byg
Gene trapped Allele Detail

Summary

• Symbol: Aggf1^Gt(PT036)Byg
• Name: angiogenic factor with G patch and FHA domains 1; gene trap PT036, BayGenomics
• MGI ID: MGI:4122569
• Synonyms: Aggf1^Geo
• Gene: Aggf1 Location: Chr13:95487191-95511860 bp, - strand Genetic Position: Chr13, 49.41 cM
• Alliance: Aggf1^Gt(PT036)Byg page

Mutation origin

• Mutant Cell Line: PT036
• Germline Transmission: Earliest citation of germline transmission: J:239252
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: pGT0pfs Vector Type: gene trap
• Mutation details: The gene-trapping vector, which contains a splicing adaptor followed by a beta-geo reporter gene, inserted into intron 11, resulting in a truncated protein with the G-patch domain and C-terminus replaced with beta-Geo that produces a fusion protein with 569 N-terminal amino acids of the gene fused to 1,327 amino acids of the beta-galactosidase-neomycin protein. (J:239252)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  PT036	BZ412820 ; (MGI Seq Detail)	5' RACE	Chr13:95492900-95493860 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  5 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aggf1 Mutation: 36 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)