Nme2^{Gt(69C10)Cmhd}
Gene trapped Allele Detail

Summary

• Symbol: Nme2^{Gt(69C10)Cmhd}
• Name: NME/NM23 nucleoside diphosphate kinase 2; gene trap 69C10, Centre for Modeling Human Disease
• MGI ID: MGI:4122609
• Synonyms: NDPK-B^-, Nme2^{Gt(CMHD-GT_69C10-3)Cmhd}
• Gene: Nme2 Location: Chr11:93840640-93847082 bp, - strand Genetic Position: Chr11, 58.88 cM, cytoband C
• Alliance: Nme2^{Gt(69C10)Cmhd} page

Mutation origin

• Mutant Cell Line: 69C10
• Germline Transmission: Earliest citation of germline transmission: J:167387
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pMS1
• Mutation details: The gene trap vector inserted between exon 3 and exon 4. The absence of protein expression was confirmed by western blot analysis on spleen plus lymph node and kidney extracts. (J:167387)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CMHD-GT_69C10-3	BZ689853 ; (MGI Seq Detail)	3' RACE	Chr11:93840642-93840873 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Nme2 Mutation: 17 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 8 reference(s)