Atg4b^{Gt(A029E06)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Atg4b^{Gt(A029E06)Wrst}
• Name: autophagy related 4B, cysteine peptidase; gene trap A029E06, German Gene Trap Consortium
• MGI ID: MGI:4123150
• Gene: Atg4b Location: Chr1:93682627-93717328 bp, + strand Genetic Position: Chr1, 47.32 cM
• Alliance: Atg4b^{Gt(A029E06)Wrst} page

Balance dysfunction and either absence of otoconial crystals or presence of abnormal otoconia in Atg4b^{Gt(A029E06)Wrst}/Atg4b^{Gt(A029E06)Wrst} mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: A029E06
• Germline Transmission: Earliest citation of germline transmission: J:163712
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pT1betageo
• Mutation details: The gene trap vector inserted between exon 1 and 2. The absence of protein expression was confirmed by western blot analysis on liver extracts. (J:163712)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  A029E06	BZ690440 ; (MGI Seq Detail)	5' RACE	Chr1:93682631-93682775 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  10 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Atg4b^{Gt(A029E06)Wrst} allele

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atg4b Mutation: 40 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 14 reference(s)