Eif4h^Gt(Ex279)Byg
Gene trapped Allele Detail

Summary

• Symbol: Eif4h^Gt(Ex279)Byg
• Name: eukaryotic translation initiation factor 4H; gene trap Ex279, BayGenomics
• MGI ID: MGI:4123901
• Synonyms: Eif4h^(EX279)
• Gene: Eif4h Location: Chr5:134648726-134668263 bp, - strand Genetic Position: Chr5, 74.71 cM
• Alliance: Eif4h^Gt(Ex279)Byg page

Mutation origin

• Mutant Cell Line: Ex279
• Germline Transmission: Earliest citation of germline transmission: J:181945
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1tfr Vector Type: gene trap
• Mutation details: The gene trap vector inserted into intron 1. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts. (J:181945)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  Ex279	CC144594 ; (MGI Seq Detail)	5' RACE	Chr5:134668094-134668179 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  39 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eif4h Mutation: 34 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)