Prcp^{Gt(KST302)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Prcp^{Gt(KST302)Byg}
• Name: prolylcarboxypeptidase (angiotensinase C); gene trap KST302, BayGenomics
• MGI ID: MGI:4123993
• Synonyms: Prcp^gt, PRCP^gt
• Gene: Prcp Location: Chr7:92524461-92583789 bp, + strand Genetic Position: Chr7, 51.64 cM, cytoband E2
• Alliance: Prcp^{Gt(KST302)Byg} page

Mutation origin

• Mutant Cell Line: KST302
• Germline Transmission: Earliest citation of germline transmission: J:152535
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1TMpfs Vector Type: secretory trap
• Mutation details: The gene trap vector pGT1TM was inserted into intron 4. The absence of transcript expression was confirmed by RT-PCR on hypothalamic and kidney extracts.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  KST302	CC144700 ; (MGI Seq Detail)	5' RACE	Chr7:92524588-92559523 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  8 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Prcp^{Gt(KST302)Byg} allele

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prcp Mutation: 33 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 13 reference(s)