Canx^{Gt(KST286)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Canx^{Gt(KST286)Byg}
• Name: calnexin; gene trap KST286, BayGenomics
• MGI ID: MGI:4123998
• Gene: Canx Location: Chr11:50184788-50216500 bp, - strand Genetic Position: Chr11, 30.46 cM
• Alliance: Canx^{Gt(KST286)Byg} page

Small size and neurological abnormalities in Canx^{Gt(KST286)Byg}/Canx^{Gt(KST286)Byg} mice

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: KST286
• Germline Transmission: Earliest citation of germline transmission: J:164553
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1TMpfs Vector Type: secretory trap
• Mutation details: The gene trap vector inserted downstream of exon 7. The absence of protein expression was confirmed by western blot analysis on fibroblast and brain extracts.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  KST286	CC144706 ; (MGI Seq Detail)	5' RACE	Chr11:50198297-50199699 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  62 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Canx^{Gt(KST286)Byg} allele

Expression

In Mice Carrying this Mutation:	42 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Canx Mutation: 55 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)