Ptbp2^{Gt(NPX210)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Ptbp2^{Gt(NPX210)Byg}
• Name: polypyrimidine tract binding protein 2; gene trap NPX210, BayGenomics
• MGI ID: MGI:4124189
• Gene: Ptbp2 Location: Chr3:119512391-119578115 bp, - strand Genetic Position: Chr3, 52.18 cM
• Alliance: Ptbp2^{Gt(NPX210)Byg} page

Mutation origin

• Mutant Cell Line: NPX210
• Germline Transmission: Earliest citation of germline transmission: J:185949
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1dTMpfs Vector Type: secretory trap
• Mutation details: The gene trap cassette inserted into intron 1. Western blot analysis of whole brain lysates from homozygous mice confirmed the absence of protein expression. (J:185949)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  NPX210	CC156029 ; (MGI Seq Detail)	5' RACE	Chr3:119576850-119576932 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  37 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptbp2 Mutation: 54 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)