Topors^{Gt(DTM034)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Topors^{Gt(DTM034)Byg}
• Name: topoisomerase I binding, arginine/serine-rich; gene trap DTM034, BayGenomics
• MGI ID: MGI:4124300
• Gene: Topors Location: Chr4:40259606-40269841 bp, - strand Genetic Position: Chr4, 20.24 cM
• Alliance: Topors^{Gt(DTM034)Byg} page

Mutation origin

• Mutant Cell Line: DTM034
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: pGT1dTMpfs Vector Type: secretory trap
• The gene was disrupted by the insertion of the pGT1dTMpfs vector into intron 2.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  DTM034	CC156155 ; (MGI Seq Detail)	5' RACE	Chr4:40268303-40268424 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  20 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Topors^{Gt(DTM034)Byg}

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Topors Mutation: 60 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)