Glg1^{Gt(RST092)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Glg1^{Gt(RST092)Byg}
• Name: golgi apparatus protein 1; gene trap RST092, BayGenomics
• MGI ID: MGI:4125299
• Synonyms: ESL-1^-
• Gene: Glg1 Location: Chr8:111881053-111985848 bp, - strand Genetic Position: Chr8, 57.98 cM
• Alliance: Glg1^{Gt(RST092)Byg} page

Mutation origin

• Mutant Cell Line: RST092
• Germline Transmission: Earliest citation of germline transmission: J:226586
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0TMpfs Vector Type: secretory trap
• Mutation details: A gene trap vector inserted into intron 1. Quantitative RT-PCR and Western blot analysis revealed significantly reduced mRNA and protein levels in spleen tissue from heterozygous mutant mice. (J:226586)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RST092	CC178679 ; (MGI Seq Detail)	5' RACE	Chr8:111985404-111985551 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  17 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Glg1 Mutation: 65 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)