Rab1a^Gt(XB498)Byg
Gene trapped Allele Detail

Summary

• Symbol: Rab1a^Gt(XB498)Byg
• Name: RAB1A, member RAS oncogene family; gene trap XB498, BayGenomics
• MGI ID: MGI:4125357
• Synonyms: Rab1a^-
• Gene: Rab1a Location: Chr11:20151432-20176856 bp, + strand Genetic Position: Chr11, 12.92 cM
• Alliance: Rab1a^Gt(XB498)Byg page

Mutation origin

• Mutant Cell Line: XB498
• Germline Transmission: Earliest citation of germline transmission: J:322487
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0pfs Vector Type: gene trap
• Mutation details: A beta-galactosidase gene was inserted between exons 2 and 3. Western blot analysis confirmed the complete absence of protein in embryo lysates from E10.5 homozygous mutant mice. (J:322487)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XB498	CC178739 ; (MGI Seq Detail)	5' RACE	Chr11:20151431-20165701 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  53 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rab1a Mutation: 33 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)