Hsp90aa1^Gt(XE444)Byg
Gene trapped Allele Detail

Summary

• Symbol: Hsp90aa1^Gt(XE444)Byg
• Name: heat shock protein 90, alpha (cytosolic), class A member 1; gene trap XE444, BayGenomics
• MGI ID: MGI:4126277
• Synonyms: Hsp90alpha^gt
• Gene: Hsp90aa1 Location: Chr12:110657470-110662829 bp, - strand Genetic Position: Chr12, 60.75 cM
• Alliance: Hsp90aa1^Gt(XE444)Byg page

Mutation origin

• Mutant Cell Line: XE444
• Germline Transmission: Earliest citation of germline transmission: J:169871
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: The gene trap vector inserted into intron 10. The absence of protein expression was confirmed by western blot analysis on brain, heart, kidney, liver, lung, muscle, pancreas, spleen, and testis extracts. (J:169871)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XE444	CC183480 ; (MGI Seq Detail)	5' RACE	multiple
  * GRCm39; (strand of gene trap mutagenesis)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Hsp90aa1^Gt(XE444)Byg

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hsp90aa1 Mutation: 41 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 8 reference(s)