Dusp4^Gt(XG164)Byg
Gene trapped Allele Detail

Summary

• Symbol: Dusp4^Gt(XG164)Byg
• Name: dual specificity phosphatase 4; gene trap XG164, BayGenomics
• MGI ID: MGI:4127030
• Gene: Dusp4 Location: Chr8:35274451-35287048 bp, + strand Genetic Position: Chr8, 21.16 cM
• Alliance: Dusp4^Gt(XG164)Byg page

Mutation origin

• Mutant Cell Line: XG164
• Germline Transmission: Earliest citation of germline transmission: J:180366
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: The gene trap vector inserted into intron 1. Northern blot analysis confirmed the absence of transcript expression in the thymus and spleen. Western blot analysis confirmed the absence of protein expression in stimulated thymocytes. (J:180366)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XG164	CC200182 ; (MGI Seq Detail)	5' RACE	Chr8:35275013-35275324 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dusp4 Mutation: 22 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)