Chd7^Gt(XK403)Byg
Gene trapped Allele Detail

Summary

• Symbol: Chd7^Gt(XK403)Byg
• Name: chromodomain helicase DNA binding protein 7; gene trap XK403, BayGenomics
• MGI ID: MGI:4127559
• Synonyms: Chd7^gt, Chd7^xk, Chd7^xk403
• Gene: Chd7 Location: Chr4:8690406-8867659 bp, + strand Genetic Position: Chr4, 3.68 cM
• Alliance: Chd7^Gt(XK403)Byg page

Pharyngeal arch artery patterning defects in Chd7^Whi/Chd7⁺, Chd7^Gt(XK403)Byg/Chd7⁺ and Chd7^Gt(XK403)Byg/Chd7⁺ Tbx1^tm1Bld/Tbx1⁺ embryos

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: XK403
• Germline Transmission: Earliest citation of germline transmission: J:154590
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: The gene trap vector containing a beta-geo cassette with a floxed splice acceptor inserted into intron 36. Cre mediated recombination of the splice acceptor can restore expression. (J:154590)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XK403	CC248927 ; (MGI Seq Detail)	5' RACE	Chr4:8863915-8864046 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  25 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Chd7^{Gt(RRR136)Byg} and Chd7^Gt(XK403)Byg gene trap constructs

Disease models

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	16 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chd7 Mutation: 138 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)