EpcamGt(RST556)Byg
Gene trapped Allele Detail
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Symbol: |
EpcamGt(RST556)Byg |
Name: |
epithelial cell adhesion molecule; gene trap RST556, BayGenomics |
MGI ID: |
MGI:4127613 |
Gene: |
Epcam Location: Chr17:87943407-87958555 bp, + strand Genetic Position: Chr17, 57.87 cM
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Alliance: |
EpcamGt(RST556)Byg page
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Developmental delay in EpcamGt(RST556)Byg/EpcamGt(RST556)Byg embryos
Show the 3 phenotype image(s) involving this allele.
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Mutant Cell Line: |
RST556 |
Germline Transmission: |
Earliest citation of germline transmission:
J:155941
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Parent Cell Line: |
Other (see notes) (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
Mutation: |
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Insertion of gene trap vector
Vector: pGT1TMpfs
Vector Type: secretory trap
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Mutation details: A gene trap insertion located in the third intron results in an in frame
fusion transcript consisting of exons 1 (untranslated region), 2, and 3, a CD2-derived transmembrane domain, beta galactosidase and neomycin. LacZ expression is detected at E8.5 in a predominantly endodermal pattern and in multiple tissues at later stages.
(J:155941)
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Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
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Generation of the EpcamGt(RST556)Byg allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Epcam Mutation: |
33 strains or lines available
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All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
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Original: |
J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008; |
All: |
3 reference(s) |
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