Nmnat2^{Gt(RRF238)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Nmnat2^{Gt(RRF238)Byg}
• Name: nicotinamide nucleotide adenylyltransferase 2; gene trap RRF238, BayGenomics
• MGI ID: MGI:4127757
• Synonyms: Nmnat2^gtBay
• Gene: Nmnat2 Location: Chr1:152830744-152995007 bp, + strand Genetic Position: Chr1, 65.15 cM
• Alliance: Nmnat2^{Gt(RRF238)Byg} page

Mutation origin

• Mutant Cell Line: RRF238
• Germline Transmission: Earliest citation of germline transmission: J:167591
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Expression in homozygous mice is reduced to about 50% that in wild-type mice. (J:200901)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRF238	CC249140 ; (MGI Seq Detail)	5' RACE	unknown
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  206 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nmnat2 Mutation: 271 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)