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Uggt1Gt(RST539)Byg
Gene trapped Allele Detail
Summary
Symbol: Uggt1Gt(RST539)Byg
Name: UDP-glucose glycoprotein glucosyltransferase 1; gene trap RST539, BayGenomics
MGI ID: MGI:4128266
Synonyms: ugt1-
Gene: Uggt1  Location: Chr1:36179109-36283407 bp, - strand  Genetic Position: Chr1, 15.15 cM
Alliance: Uggt1Gt(RST539)Byg page
Mutation
origin
Mutant Cell Line:  RST539
Germline Transmission:  Earliest citation of germline transmission: J:255869
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout)
Mutation:    Insertion of gene trap vector     Vector: pGT0TMpfs     Vector Type: secretory trap
 
Mutation detailsThe pGT0TMpfs gene trap, containing CD4 transmembrane domain/beta-galactosidase, neomycin phosphotransferase reporter fusion protein (beta-geo), inserted in intron 13. This truncates the coding region of the gene before exon 14 at codon 459 (versus 1551 wild-type). The catalytic domain is encoded by exons 34-41 so this yields a null allele. Immunoblots confirm that no peptide is produced from this allele. (J:255869)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Uggt1 Mutation:  101 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory