Foxj3^Gt(XL913)Byg
Gene trapped Allele Detail

Summary

• Symbol: Foxj3^Gt(XL913)Byg
• Name: forkhead box J3; gene trap XL913, BayGenomics
• MGI ID: MGI:4128374
• Synonyms: Foxj3^m/m
• Gene: Foxj3 Location: Chr4:119396858-119486316 bp, + strand Genetic Position: Chr4, 55.43 cM
• Alliance: Foxj3^Gt(XL913)Byg page

Mutation origin

• Mutant Cell Line: XL913
• Germline Transmission: Earliest citation of germline transmission: J:157260
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: A gene trap was created by the insertion of a beta-galactosidase/neomyocin cassette and two splice acceptors into intron 5. The predicted mRNA contains exons 1 through 5. Semi-quantitative RT-PCR of gastrocnemius skeletal muscle revealed that expression of the transcript is limited to exons 1-5, and that the carboxy-terminal activation domain in exons 8-12 are not transcribed. (J:157260)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XL913	CC325176 ; (MGI Seq Detail)	5' RACE	Chr4:119430785-119459687 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  24 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxj3 Mutation: 55 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)