Stau2^{Gt(RRG396)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Stau2^{Gt(RRG396)Byg}
• Name: staufen double-stranded RNA binding protein 2; gene trap RRG396, BayGenomics
• MGI ID: MGI:4128933
• Synonyms: Stau2^GT
• Gene: Stau2 Location: Chr1:16298898-16590336 bp, - strand Genetic Position: Chr1, 5.05 cM, cytoband A3
• Alliance: Stau2^{Gt(RRG396)Byg} page

Mutation origin

• Mutant Cell Line: RRG396
• Germline Transmission: Earliest citation of germline transmission: J:284920
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Hypomorph)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. Immunostaining against Stau2 in frontal cerebellar sections revealed a 50% reduction of protein intensity in cerebellar Purkinje cells of adult homozygous mutant mice. (J:284920)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRG396	CC325807 ; (MGI Seq Detail)	5' RACE	Chr1:16460046-16510572 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stau2 Mutation: 33 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)