Steep1^{Gt(RRG250)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Steep1^{Gt(RRG250)Byg}
• Name: STING1 ER exit protein 1; gene trap RRG250, BayGenomics
• MGI ID: MGI:4128982
• Gene: Steep1 Location: ChrX:36087388-36127956 bp, - strand Genetic Position: ChrX, 21.23 cM, cytoband A2
• Alliance: Steep1^{Gt(RRG250)Byg} page

Steep1^{Gt(RRG250)Byg}/Y chimera at E9.5 exhibits abnormal brain development

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: RRG250
• Germline Transmission: Earliest citation of germline transmission: J:160967
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: Sequence tags for this gene trap insertion either do not align with the reference mouse genome, or align in multiple locations.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRG250	CC325862 ; (MGI Seq Detail)	5' RACE	multiple
  * GRCm39; (strand of gene trap mutagenesis)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Steep1 Mutation: 24 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

Additional information on the construction of chimeric mice reported in J:160967 can be found at this link

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)