Cdk5rap2^{Gt(RRF465)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Cdk5rap2^{Gt(RRF465)Byg}
• Name: CDK5 regulatory subunit associated protein 2; gene trap RRF465, BayGenomics
• MGI ID: MGI:4129121
• Gene: Cdk5rap2 Location: Chr4:70135092-70328672 bp, - strand Genetic Position: Chr4, 35.92 cM, cytoband C2
• Alliance: Cdk5rap2^{Gt(RRF465)Byg} page

Mutation origin

• Mutant Cell Line: RRF465
• Germline Transmission: Earliest citation of germline transmission: J:163849
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: The gene trap vector inserted into intron 12. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblasts extracts. (J:163849)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRF465	CC326014 ; (MGI Seq Detail)	5' RACE	Chr4:70255577-70271889 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  19 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdk5rap2 Mutation: 87 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)