Ctnnal1^{Gt(RRJ603)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Ctnnal1^{Gt(RRJ603)Byg}
• Name: catenin alpha like 1; gene trap RRJ603, BayGenomics
• MGI ID: MGI:4129892
• Synonyms: alpha-catulin KD
• Gene: Ctnnal1 Location: Chr4:56810935-56865188 bp, - strand Genetic Position: Chr4, 31.66 cM, cytoband C1
• Alliance: Ctnnal1^{Gt(RRJ603)Byg} page

Mutation origin

• Mutant Cell Line: RRJ603
• Germline Transmission: Earliest citation of germline transmission: J:308883
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Hypomorph)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: The gene trap vector pGT2Lxf inserted in intron 1 of the gene. sqRT-PCR analysis revealed low levels of expression in some E10.5 homozygous mutant embryos, indicating that this is a hypomorphic allele.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRJ603	CC798993 ; (MGI Seq Detail)	5' RACE	Chr4:56864979-56865164 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  96 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	47 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctnnal1 Mutation: 176 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)