Sdccag8^{Gt(OST40418)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Sdccag8^{Gt(OST40418)Lex}
• Name: serologically defined colon cancer antigen 8; gene trap OST40418, Lexicon Genetics
• MGI ID: MGI:4156902
• Synonyms: Sdccag8^gt
• Gene: Sdccag8 Location: Chr1:176642226-176848003 bp, + strand Genetic Position: Chr1, 82.66 cM, cytoband H3
• Alliance: Sdccag8^{Gt(OST40418)Lex} page

Mutation origin

• Mutant Cell Line: OST40418
• Germline Transmission: Earliest citation of germline transmission: J:226661
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap cassette inserted in to intron 1. The absence of transcribed mRNA was verified by quantitative RT-PCR analysis using RNA isolated from embryonic day 13.5 (E13.5) mouse embryonic fibroblasts. Immunoblotting confirmed the absence of encoded protein from lung and kidney lysates of homozygous mutant mice. (J:226661)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST40418	CG498826 ; (MGI Seq Detail)	3' RACE	Chr1:176652329-176652607 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sdccag8 Mutation: 36 strains or lines available

Notes

Phenotypic Similarity to Human Syndrome: Nephronophthisis Type 10 (J:226661)

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)