Tmem218^{Gt(OST40451)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Tmem218^{Gt(OST40451)Lex}
• Name: transmembrane protein 218; gene trap OST40451, Lexicon Genetics
• MGI ID: MGI:4156922
• Gene: Tmem218 Location: Chr9:37119519-37134524 bp, + strand Genetic Position: Chr9, 20.74 cM
• Alliance: Tmem218^{Gt(OST40451)Lex} page

Mutation origin

• Mutant Cell Line: OST40451
• Germline Transmission: Earliest citation of germline transmission: J:227399
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector inserted into intron 1. RT-PCR analysis on RNA derived from kidney and spleen showed that no detectable wild-type transcript is produced from this allele. (J:227399)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST40451	CG498846 ; (MGI Seq Detail)	3' RACE	Chr9:37129561-37133908 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  4 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tmem218 Mutation: 6 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)