Lrba^{Gt(OST69142)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Lrba^{Gt(OST69142)Lex}
• Name: LPS-responsive beige-like anchor; gene trap OST69142, Lexicon Genetics
• MGI ID: MGI:4173110
• Synonyms: LRBA^-
• Gene: Lrba Location: Chr3:86131987-86689999 bp, + strand Genetic Position: Chr3, 37.83 cM, cytoband F1
• Alliance: Lrba^{Gt(OST69142)Lex} page

Mutation origin

• Mutant Cell Line: OST69142
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap targeting vector (consisting of a splice acceptor sequence (SA) followed by a beta-geo selection cassette and a polyadenylation signal) integrated into the intron between exons 2 and 3. Northern blot of kidney and brain confirmed that homozygous mice lack detectable mRNA.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST69142	CG515090 ; (MGI Seq Detail)	3' RACE	Chr3:86317187-86317277 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  9 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lrba Mutation: 139 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)