Adrm1^{Gt(OST128063)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Adrm1^{Gt(OST128063)Lex}
• Name: adhesion regulating molecule 1 26S proteasome ubiquitin receptor; gene trap OST128063, Lexicon Genetics
• MGI ID: MGI:4196174
• Synonyms: Rpn13^-
• Gene: Adrm1 Location: Chr2:179813381-179818076 bp, + strand Genetic Position: Chr2, 102.69 cM
• Alliance: Adrm1^{Gt(OST128063)Lex} page

Decreased body weight in early life and higher body fat content in Adrm1^{Gt(OST128063)Lex}/Adrm1^{Gt(OST128063)Lex} mice

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: OST128063
• Germline Transmission: Earliest citation of germline transmission: J:166694
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted downstream of the exon containing the translation start site. The absence of protein expression was confirmed by immunohistochemistry of the thymus. (J:166694)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST128063	CG538269 ; (MGI Seq Detail)	3' RACE	Chr2:179814646-179817050 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  5 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Adrm1 Mutation: 22 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)