Arhgap26^{Gt(OST135790)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Arhgap26^{Gt(OST135790)Lex}
• Name: Rho GTPase activating protein 26; gene trap OST135790, Lexicon Genetics
• MGI ID: MGI:4199843
• Synonyms: GRAF1^gt, GRAF^gt
• Gene: Arhgap26 Location: Chr18:38734531-39509338 bp, + strand Genetic Position: Chr18, 20.51 cM, cytoband B3
• Alliance: Arhgap26^{Gt(OST135790)Lex} page

Mutation origin

• Mutant Cell Line: OST135790
• Germline Transmission: Earliest citation of germline transmission: J:215392
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Hypomorph)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted in intron 1. RT-PCR and western blot analysis indicated reduced RNA and protein expression in homozygous pups at P7.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST135790	CG541955 ; (MGI Seq Detail)	3' RACE	Chr18:39230680-39244904 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  4 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arhgap26 Mutation: 50 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)