Nosip^{Gt(OST138992)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Nosip^{Gt(OST138992)Lex}
• Name: nitric oxide synthase interacting protein; gene trap OST138992, Lexicon Genetics
• MGI ID: MGI:4201195
• Gene: Nosip Location: Chr7:44711853-44727634 bp, + strand Genetic Position: Chr7, 29.1 cM, cytoband B2
• Alliance: Nosip^{Gt(OST138992)Lex} page

Mutation origin

• Mutant Cell Line: OST138992
• Germline Transmission: Earliest citation of germline transmission: J:245546
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped
• Mutation: Insertion of gene trap vector
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. The splice site-flanked gene trap cassette was inserted into the second intron. Immunoblotting confirmed the absence of protein from heads of embryos. (J:245546)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST138992	CG543309 ; (MGI Seq Detail)	3' RACE	Chr7:44723409-44725754 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  155 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Mice Carrying this Mutation:	9 assay results
In Structures Affected by this Mutation:	15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nosip Mutation: 48 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)