Plagl1^{Gt(OST181461)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Plagl1^{Gt(OST181461)Lex}
• Name: pleiomorphic adenoma gene-like 1; gene trap OST181461, Lexicon Genetics
• MGI ID: MGI:4218514
• Gene: Plagl1 Location: Chr10:12966576-13007438 bp, + strand Genetic Position: Chr10, 4.72 cM
• Alliance: Plagl1^{Gt(OST181461)Lex} page

Mutation origin

• Mutant Cell Line: OST181461
• Germline Transmission: Earliest citation of germline transmission: J:171037
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Sequence tags for this gene trap insertion either do not align with the reference mouse genome, or align in multiple locations. However, the gene trapping vector was reported to insert at the third intron of the Zac1 gene as detected by inverse-PCR. No protein expression is observed in homozygote or in heterozygotes descended from mutant males. (J:171037)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST181461	CG560676 ; (MGI Seq Detail)	3' RACE	multiple
  * GRCm39; (strand of gene trap mutagenesis)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plagl1 Mutation: 32 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)