Pa2g4^{Gt(OST186047)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Pa2g4^{Gt(OST186047)Lex}
• Name: proliferation-associated 2G4; gene trap OST186047, Lexicon Genetics
• MGI ID: MGI:4220888
• Gene: Pa2g4 Location: Chr10:128393635-128401803 bp, - strand Genetic Position: Chr10, 77.09 cM, cytoband D3
• Alliance: Pa2g4^{Gt(OST186047)Lex} page

Growth retardation of Pa2g4^{Gt(OST186047)Lex}/Pa2g4^{Gt(OST186047)Lex} mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: OST186047
• Germline Transmission: Earliest citation of germline transmission: J:151280
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted into intron 2. The predicted protein is truncated after the first 20 amino acids, which have no known biological function. The absence of transcript expression was confirmed by RT-PCR on E12.5 embryo fibroblasts. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblasts. (J:151280)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST186047	CG563062 ; (MGI Seq Detail)	3' RACE	Chr10:128396560-128399575 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  16 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pa2g4 Mutation: 17 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)