Ppp1r2^{Gt(OST190571)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Ppp1r2^{Gt(OST190571)Lex}
• Name: protein phosphatase 1, regulatory inhibitor subunit 2; gene trap OST190571, Lexicon Genetics
• MGI ID: MGI:4223448
• Gene: Ppp1r2 Location: Chr16:31070359-31094095 bp, - strand Genetic Position: Chr16, 21.41 cM, cytoband B2
• Alliance: Ppp1r2^{Gt(OST190571)Lex} page

Mutation origin

• Mutant Cell Line: OST190571
• Germline Transmission: Earliest citation of germline transmission: J:227697
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted in intron 1. Western blot analysis confirmed the absence of protein in homozygous embryos at E10.5. (J:227697)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST190571	CG565628 ; (MGI Seq Detail)	3' RACE	Chr16:31077153-31084231 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  11 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp1r2 Mutation: 10 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)