Lix1^{Gt(OST262711)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Lix1^{Gt(OST262711)Lex}
• Name: limb and CNS expressed 1; gene trap OST262711, Lexicon Genetics
• MGI ID: MGI:4256026
• Gene: Lix1 Location: Chr17:17622948-17679649 bp, + strand Genetic Position: Chr17, 9.77 cM, cytoband A3.1
• Alliance: Lix1^{Gt(OST262711)Lex} page

Mutation origin

• Mutant Cell Line: OST262711
• Germline Transmission: Earliest citation of germline transmission: J:185492
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector inserted into intron 1. RT-PCR analysis of spinal cord RNA confirmed that no detectable full length transcript is expressed from this allele. Reverse transcriptase-PCR amplification of spinal cord RNA identified a Lix1 alternative transcript beginning in intron 4 and containing exons 5 and 6. The alternative transcript appeared to be rodent specific, and its expression was not disrupted in homozygous KO mice. (J:185492)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST262711	CG598314 ; (MGI Seq Detail)	3' RACE	Chr17:17647415-17674599 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  19 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lix1 Mutation: 27 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)