Sppl3^{Gt(OST279815)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Sppl3^{Gt(OST279815)Lex}
• Name: signal peptide peptidase 3; gene trap OST279815, Lexicon Genetics
• MGI ID: MGI:4261988
• Gene: Sppl3 Location: Chr5:115149204-115236849 bp, + strand Genetic Position: Chr5, 55.99 cM, cytoband F
• Alliance: Sppl3^{Gt(OST279815)Lex} page

Mutation origin

• Mutant Cell Line: OST279815
• Germline Transmission: Earliest citation of germline transmission: J:161922
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Retroviral insertion occurred between coding exons 6 and 7 (NCBI accession AK014709.1). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:161922)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST279815	CG604291 ; (MGI Seq Detail)	3' RACE	multiple
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  74 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sppl3 Mutation: 75 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)