Pi16^{Gt(OST292194)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Pi16^{Gt(OST292194)Lex}
• Name: peptidase inhibitor 16; gene trap OST292194, Lexicon Genetics
• MGI ID: MGI:4267708
• Gene: Pi16 Location: Chr17:29537770-29547876 bp, + strand Genetic Position: Chr17, 15.22 cM, cytoband B1
• Alliance: Pi16^{Gt(OST292194)Lex} page

Mutation origin

• Mutant Cell Line: OST292194
• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The Pi16 gene consists of 7 exons. Retroviral insertion disrupted the gene in the intron between coding exons 2 and 3 (NCBI accession NM_023734.2). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:94077)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST292194	CG610029 ; (MGI Seq Detail)	3' RACE	Chr17:29544867-29547647 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  3 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pi16 Mutation: 30 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)