Primpol^{Gt(OST296220)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Primpol^{Gt(OST296220)Lex}
• Name: primase and polymerase (DNA-directed); gene trap OST296220, Lexicon Genetics
• MGI ID: MGI:4268998
• Gene: Primpol Location: Chr8:47028629-47070247 bp, - strand Genetic Position: Chr8, 26.39 cM
• Alliance: Primpol^{Gt(OST296220)Lex} page

Mutation origin

• Mutant Cell Line: OST296220
• Germline Transmission: Earliest citation of germline transmission: J:203417
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. A splice-acceptor-neo cassette, followed by Pgk1-Btk with stop codons and splice-donor were inserted in the first intron. Quantitative PCR analysis demonstrated the absence of PRIMPOL expression. (J:203417)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST296220	CG611324 ; (MGI Seq Detail)	3' RACE	Chr8:47058118-47065460 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  4 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Primpol Mutation: 48 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)