Mpzl1^{Gt(OST332232)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Mpzl1^{Gt(OST332232)Lex}
• Name: myelin protein zero-like 1; gene trap OST332232, Lexicon Genetics
• MGI ID: MGI:4283287
• Gene: Mpzl1 Location: Chr1:165419809-165462107 bp, - strand Genetic Position: Chr1, 72.94 cM
• Alliance: Mpzl1^{Gt(OST332232)Lex} page

Mutation origin

• Mutant Cell Line: OST332232
• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The Mpzl1 gene consists of 6 exons. Retroviral insertion disrupted the gene between coding exons 1 and 2 (Accession AK090278). (J:94077)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST332232	CG625644 ; (MGI Seq Detail)	3' RACE	Chr1:165433137-165436158 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  21 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mpzl1 Mutation: 21 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
• All: 3 reference(s)