Grhpr^{Gt(OST383093)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Grhpr^{Gt(OST383093)Lex}
• Name: glyoxylate reductase/hydroxypyruvate reductase; gene trap OST383093, Lexicon Genetics
• MGI ID: MGI:4301247
• Gene: Grhpr Location: Chr4:44981395-44990734 bp, + strand Genetic Position: Chr4, 23.65 cM, cytoband B2
• Alliance: Grhpr^{Gt(OST383093)Lex} page

Mutation origin

• Mutant Cell Line: OST383093
• Germline Transmission: Earliest citation of germline transmission: J:181969
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted into intron 1. Western blot analysis confirmed the absence of protein expression in the brain, heart, liver, kidney and testes. (J:181969)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST383093	CG643659 ; (MGI Seq Detail)	3' RACE	Chr4:44982882-44986376 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Grhpr Mutation: 19 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)