Ywhaz^{Gt(OST432062)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Ywhaz^{Gt(OST432062)Lex}
• Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; gene trap OST432062, Lexicon Genetics
• MGI ID: MGI:4315078
• Synonyms: 14-3-3zeta^-, 14-3-3zeta^062-, 14-3-3zeta^{Gt(OST062)Lex}
• Gene: Ywhaz Location: Chr15:36771014-36797173 bp, - strand Genetic Position: Chr15, 14.56 cM
• Alliance: Ywhaz^{Gt(OST432062)Lex} page

Mutation origin

• Mutant Cell Line: OST432062
• Germline Transmission: Earliest citation of germline transmission: J:217297
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The beta-geo gene trap inserted into the first intron. Western blot analysis confirmed the absence of protein expression in embryonic and adult brain tissue. (J:217297)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST432062	CG657541 ; (MGI Seq Detail)	3' RACE	Chr15:36772919-36775824 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  14 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Ywhaz Mutation: 31 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 9 reference(s)