Pdlim7^{Gt(OST445990)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Pdlim7^{Gt(OST445990)Lex}
• Name: PDZ and LIM domain 7; gene trap OST445990, Lexicon Genetics
• MGI ID: MGI:4319956
• Synonyms: Pdlim7^{Gt(VICTR37)445990Lex}
• Gene: Pdlim7 Location: Chr13:55645300-55661281 bp, - strand Genetic Position: Chr13, 30.06 cM, cytoband B2
• Alliance: Pdlim7^{Gt(OST445990)Lex} page

Mild cardiac dysfunction with increased valve annulus dimensions in Pdlim7^{Gt(OST445990)Lex}/Pdlim7^{Gt(OST445990)Lex} adults

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: OST445990
• Germline Transmission: Earliest citation of germline transmission: J:209780
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The beta-geo containing gene trap vector inserted into intron 2. Western blot analysis confirmed the absence of protein expression in the uterus. Immunohistochemistry confirmed the absence of protein expression in the aorta. (J:209780)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST445990	CG662435 ; (MGI Seq Detail)	3' RACE	Chr13:55654876-55656857 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  12 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Pdlim7^{Gt(OST445990)Lex} allele

Expression

In Mice Carrying this Mutation:	60 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pdlim7 Mutation: 20 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)