Mkln1^{Gt(OST448976)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Mkln1^{Gt(OST448976)Lex}
• Name: muskelin 1, intracellular mediator containing kelch motifs; gene trap OST448976, Lexicon Genetics
• MGI ID: MGI:4321123
• Gene: Mkln1 Location: Chr6:31375670-31493746 bp, + strand Genetic Position: Chr6, 12.57 cM, cytoband B1-B2
• Alliance: Mkln1^{Gt(OST448976)Lex} page

Mutation origin

• Mutant Cell Line: OST448976
• Germline Transmission: Earliest citation of germline transmission: J:174709
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted into intron 1. Western blot analysis confirmed the absence of protein expression in brain extracts. (J:174709)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST448976	CG663607 ; (MGI Seq Detail)	3' RACE	Chr6:31403702-31408148 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  10 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mkln1 Mutation: 57 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)