Serinc1^{Gt(OST454985)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Serinc1^{Gt(OST454985)Lex}
• Name: serine incorporator 1; gene trap OST454985, Lexicon Genetics
• MGI ID: MGI:4323314
• Gene: Serinc1 Location: Chr10:57391870-57408573 bp, - strand Genetic Position: Chr10, 29.19 cM
• Alliance: Serinc1^{Gt(OST454985)Lex} page

Mutation origin

• Mutant Cell Line: OST454985
• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The Serinc1 gene consists of 9 exons. Retroviral insertion disrupted the gene in the intron between coding exons 1 and 2 (NCBI accession NM_019760.1). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:94077)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST454985	CG665803 ; (MGI Seq Detail)	3' RACE	Chr10:57401310-57403923 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  4 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Serinc1 Mutation: 21 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)