Asnsd1^{Gt(OST460318)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Asnsd1^{Gt(OST460318)Lex}
• Name: asparagine synthetase domain containing 1; gene trap OST460318, Lexicon Genetics
• MGI ID: MGI:4324901
• Synonyms: Asnsd1^-
• Gene: Asnsd1 Location: Chr1:53383776-53391911 bp, - strand Genetic Position: Chr1, 26.99 cM, cytoband C1
• Alliance: Asnsd1^{Gt(OST460318)Lex} page

Mutation origin

• Mutant Cell Line: OST460318
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted within the 5' untranslated region of the gene and is expected to prevent both transcription and translation of the endogenous transcript. RT-PCR analysis confirmed the absence of endogenous transcript in kidney and liver tissue from homozygous mutant mice. (J:320329)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST460318	CG667396 ; (MGI Seq Detail)	3' RACE	Chr1:53387560-53390083 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Asnsd1 Mutation: 28 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)